Authored on 28 April 2025 by Mr Adeel Arshad,
Medically reviewed 30 April 2026 by Dr Ruch Karunadasa.
Next review due: 30 April 2027
Compare UK weight loss treatments
Prescription medicines online after a clinician reviews your consultation — with fast, discreet delivery from a CQC-registered UK service
Wegovy (Semaglutide)
Wegovy is a once-weekly injection that you administer to yourself to aid weight loss. It contains the active substance semaglutide which mimics a natural hormone in the body called glucagon-like peptide-1 (GLP-1) which helps reduce appetite and increase feelings of fullness.
Wegovy is a once-weekly injection that you administer to yourself to aid weight loss. It contains the active substance semaglutide which mimics a natural hormone in the body called glucagon-like peptide-1 (GLP-1) which helps reduce appetite and increase feelings of fullness.
Wegovy Pill (Oral semaglutide)
Wegovy Pill is an oral prescription medicine containing semaglutide for weight management in adults when a clinician considers it appropriate, together with diet and increased physical activity. It is taken as tablets on a titrated schedule rather than as a weekly injection.
Wegovy Pill is an oral prescription medicine containing semaglutide for weight management in adults when a clinician considers it appropriate, together with diet and increased physical activity.
Mounjaro (Tirzepatide)
Mounjaro is an injectable prescription medicine used in conjunction with diet and exercise to enhance blood sugar (glucose) levels in adults with type 2 diabetes mellitus.
Mounjaro is an injectable prescription medicine used in conjunction with diet and exercise to enhance blood sugar (glucose) levels in adults with type 2 diabetes mellitus.
Nevolat (generic Saxenda)
Nevolat (generic Saxenda) is a once-daily injection that you administer to yourself to aid weight loss. It contains the active ingredient liraglutide, which is very similar to a naturally occurring hormone in your body called GLP-1. It works by making you feel less hungry, slowing down the emptying of your stomach and making you feel ‘fuller’ for longer.
Mysimba (Naltrexone & Bupropion)
Mysimba is a prescription-only weight-loss medication containing naltrexone and bupropion. You take 1-2 tablets once or twice a day up to a maximum of 4 tablets per day. Bupropion helps to reduce your appetite so that you do not feel as hungry and are satisfied with less food. Naltrexone is thought to curb your food cravings which reduces your desire to eat.
Saxenda
Saxenda is a once-daily injection that you administer to yourself to aid weight loss. It contains the active ingredient liraglutide, which is very similar to a naturally occurring hormone in your body called GLP-1. It works by making you feel less hungry, slowing down the emptying of your stomach and making you feel ‘fuller’ for longer.
Saxenda is out of stock. Nevolat, which has the same active ingredient, is available. Switch with no break in treatment
Orlistat (Generic Xenical)
Orlistat is a prescription-only weight-loss medication. The usual dose is one 120mg capsule taken with each of your three main meals per day. It works by reducing the absorption of fat from your diet and is very effective in weight loss when used in conjunction with exercise and a low-calorie diet.
Xenical (Orlistat)
Xenical is a prescription-only weight-loss medication containing the active ingredient orlistat. The usual dose is one 120mg capsule taken with each of your three main meals per day. It works by reducing the absorption of fat from your diet and is very effective in weight loss when used in conjunction with exercise and a low-calorie diet.
Understanding obesity
Obesity is a long-term health condition linked to increased risk of type 2 diabetes, heart disease, high blood pressure, and stroke. Body mass index (BMI) is commonly used in the UK to classify overweight (BMI 25-29.9) and obesity (BMI 30 and above).
Read our full guide to what obesity is, including causes, lifestyle support, and when prescription treatment may be appropriate, or calculate your BMI to see where you sit on the scale.
