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Adeel Arshad

Authored on 24 January 2024 by Adeel Arshad,

Reviewed 24 January 2024 by Dr Ruch Karunadasa.

Evorel Sequi Patches

HRT medication

Hormone Replacement Therapy (HRT) for women who still have a womb and have had the menopause (postmenopausal) or who are around the time of the menopause (perimenopausal). It is also used to prevent osteoporosis in women who have had the menopause and are most likely to have bone problems.

Medication effect duration

Like any other prescription medication you must consult a doctor before using it. PrivateDoc offers a confidential free consultation service that may result in you receiving a prescription for Evorel Sequi Patches if it is deemed appropriate and Evorel Sequi Patches can prescribed safely.

Consultation for HRT

Complete a 100% free and secure consultation to explore your treatment options. How our online prescription consultation works.

What are Evorel Sequi Patches?

Evorel Sequi is used for the symptoms of the menopause. It is only used in women who still have a womb. It is suitable for women who have had the menopause (postmenopausal) or who are around the time of the menopause (perimenopausal).

It is also used to prevent osteoporosis (fragile bones) in women who have had the menopause and are most likely to have bone problems. Evorel Sequi is only used if other medicines for osteoporosis have been tried first and they have not worked

How much do Evorel Sequi Patches cost?

How do you use Evorel Sequi patches?

Evorel Sequi patches are applied to the skin twice weekly. Evorel Sequi should be applied to the skin as soon as it is removed from the wrapper. Recommended application sites are on clean, dry, healthy, intact skin and each application should be made to a slightly different area of skin on the trunk below waistline. Evorel should not be applied on or near the breasts, on the same area of skin twice in a row, under elasticated areas or a tight waistband. Most women prefer to wear the patch on the thigh or bottom.

Evorel Sequi patches should remain in place during bathing and showering. Should it fall off during bathing or showering the patient should wait until he skin cools before applying a replacement patch. Should a patch fall off at other times it should be replaced immediately.

If you forget to change the patch, change it as soon as you remember and then keep to your original 'patchchange' days. You may get some bleeding and spotting like a period during this time.

Read the Patient Information Leaflet

If you use more Evorel Sequi than you should

It is unlikely that you will have too much of the hormones in Evorel Sequi. The most common symptoms of having too much oestrogen or progestogen in your body are:

  • Tender breasts
  • Feeling sick (nausea) or being sick
  • Unexpected vaginal bleeding
  • Feeling depressed
  • Tiredness
  • Acne
  • Growth of body or facial hair

Removing the patch can reverse the effects of too much oestrogen and/or progestogen. Talk to your doctor or pharmacist before using any more patches.

Contraception while using Evorel Sequi

The levels of hormone from the patches are too low to act as a contraceptive. Use non-hormonal contraceptive methods (such as a condom, diaphragm or coil) until your periods have completely stopped.

Side effects

Very common (1 in 10 people or more):

  • Irritated, itchy, red skin and rash where the patch is applied

Common (1 in 10 people or less):

  • Feeling depressed or nervous
  • Inappropriate signs of emotion
  • Being unable to sleep
  • Headache
  • Itchy skin or red rash
  • Feeling sick (nausea), or having stomach pain wind or other stomachupsets
  • Diarrhoea
  • Pain including pain in the back, muscles, joints
  • Breast pain
  • Feeling generally unwell
  • Weight gain
  • Heavy vaginal bleeding, painful periods
  • Water retention or build-up of fluid under the skin (oedema)

Uncommon (1 in 100 people or less):

  • Concentration problems
  • Feeling dizzy
  • More or less interest in sex than usual
  • Allergic reaction (hypersensitivity)
  • A fungal infection called thrush
  • Feeling tired
  • Being aware of your heartbeat (palpitations)
  • Numb or tingling hands or feet, less skin sensitivity
  • Breast lumps (non-cancerous)
  • Fuller breasts
  • Irregular vaginal bleeding
  • Thickening of the lining of the womb

Frequency not known:

  • Mood swings
  • Bloated feeling
  • Gallstones
  • Swelling of the hands and feet (peripheral oedema)
  • Puffy skin where the patch is applied

This is only a summary, please refer to patient information leaflet provided or link below for comprehensive list. Patient Information Leaflet

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Do not use Evorel Sequi if:

  • You are allergic to anything in the patches (listed in section 7below)
  • You have (or have ever had) or think you may have breast cancer
  • You have (or are suspected of having) or ever had a cancer that is made worse by oestrogens (such as endometrial cancer)
  • You have a thickening of the lining of the womb which has not been treated (endometrial hyperplasia)
  • You have vaginal bleeding you cannot explain
  • You have ever had blood clots in a vein (thrombosis) such as in the legs (deep vein thrombosis) or a blood clot that has travelled to your lung (pulmonary embolism)
  • You have problems with your blood which increases the likelihood of developing a blood clot (thrombosis) (such as protein C, protein S or antithrombin deficiency)
  • You have ever had blocked arteries (arterial thrombo-embolic disease) that gave you angina or a heart attack or astroke
  • You have (or have ever had) a liver disease and your liver functiontests have not returned to normal
  • You have a blood problem called "porphyria"
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