Epiduo Gel

Epiduo Gel is a prescription-only treatment containing benzoyl peroxide and adapalene.  It is intended to be used as a once daily treatment for Acne.

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Like any other prescription medication you must consult a doctor before using Epiduo Gel.

PrivateDoc offers a confidential free consultation service that may result in you receiving a prescription for Epiduo Gel if it is deemed appropriate and Epiduo Gel can prescribed safely.

Complete a 100% free and secure consultation to explore your treatment options.

Epiduo Gel is comprised of two ingredients.  1 gram of gel contains - 

1mg of adapalene (0.1%)

25mg of benzyl peroxide (2.5%)

Epiduo is presented in a GEL form

The gel is opaque with a white to pale yellow colour

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What is Epiduo Gel

Epiduo is used for the treatment of acne in adults and adolescents over the age of 9.

This gel combines two active ingredients, Adapalene and Benzoyl peroxide which work together but in different ways:-

  • Adapalene belongs to a group of products known as retinoids and acts specifically on the skin processes that cause acne.
  • The other active ingredient, benzoyl peroxide, works as an antimicrobial agent and by softening and peeling the outer layer of the skin.

Who can use Epiduo Gel

PrivateDoc will prescribe Epiduo Gel for those suffering from mild to moderate Acne where suitable.

Epiduo Gel should be used with caution by people with sensitive skin.

Do not use Epiduo Gel if you are allergic to the active substances or any of the other excipients of this medicine.

Epiduo should be avoided in pregnancy.  In the case of an unexpected preganacy, treatment with Epiduo should be discontinued.

Warnings and precautions:-

  • You should not use Epiduo on areas where you have cuts, scrapes or eczema.
  • Make sure Epiduo does not get into your eyes, mouth or nostrils, and other very sensitive areas of the body. Should this occur wash these areas immediately with plenty of warm water.
  • Avoid excessive exposure to sunlight and UV lamps.
  • Avoid getting Epiduo on your hair or coloured fabrics as it may bleach them and wash your hands thoroughly after you have used the medicine.

How to use Epiduo Gel

  • Wash your hands.
  • Apply a thin film of gel evenly over acne affected areas once a day at bedtime, avoiding the eyes, lips and nostrils.
  • The skin should be clean and dry before application.
  • Wash your hands after using the gel.

Important information about Epiduo Gel:-

  • This gel is for external use on the skin only.
  • Clean and dry the affected area of skin thoroughly before applying this medicine. Use mild soap and pat rather than rub the skin dry. Using clean fingertips, only apply enough medicine to cover the affected areas of skin lightly.
  • Do not apply this medicine to broken or irritated skin, or areas affected by eczema.  
  • Avoid getting this gel in contact with the eyes, eyelids, nostrils, mouth, lips, mucous membranes (eg inside of the nose) and broken areas of skin. If you accidentally get the gel on these areas, carefully wash it off with water.
  • When you first start using this medicine it may cause temporary stinging or a feeling of warmth in the skin. When used correctly, it will usually make your skin slightly red, like mild sunburn. You shouldn't use the medicine any more frequently than directed by your doctor, as this won't make it any more effective or work any quicker. It may also make your skin very red or irritated or start peeling.
  • If you get any severe redness, swelling, itching, burning sensations, blistering, crusting or peeling of your skin after using the medicine, you should apply the medicine less frequently or stop using it temporarily. If the irritation persists you should stop using the medicine completely and consult your doctor.
  • You can use cosmetics or moisturisers while using this medicine, but you should not apply them at the same time. Wash your skin thoroughly before applying the medicine. You can use cosmetics and moisturisers after the medicine has been absorbed into your skin.
  • Avoid exposure to sunlight, sunlamps or sunbeds while using this medicine, as it increases the sensitivity of your skin to UV light. If exposure to sunlight cannot be avoided, use protective measures such as sunscreens or protective clothing over the areas of skin you have treated with this medicine.
  • If your skin is sunburnt you should not use this medicine until your skin is fully recovered, as it may potentially cause severe irritation to the skin. • This preparation may bleach hair and fabrics.
  • Epiduo gel contains propylene glycol, which may cause skin irritation.

Possible side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Common (affect between 1 in 10 and 1 in 100 people)

  • Dry skin.
  • Irritant contact dermatitis.
  • Skin irritation and burning.

For further information and a full list of possible side effects please see Patient information leaflet