Mirvaso

Pfizer

The gel contains Brimonidine tartrate which is indicated for the symptomatic treatment of facial erythema of rosacea in adults.

Brimonidine tartrate is a highly selective alpha‑2 adrenergic receptor agonist, with potent vasoconstrictive and vasostabilising activity meaning Mirvaso reduces facial flushing and redness by reducing bloodflow to the area.

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What is Rosacea

Rosacea is a common skin condition mainly affecting the facial area.  It is a relapsing condition meaning that the severity of symptoms can worsen and appear more severe, whereas at other times they will improve.

Because of the nature of the condition and its affect on personal appearance, Rosacea can cause significant psychological stress and social issues if left untreated.

Symptoms of Rosacea

Most patients have periods of time where their symptoms are more troublesome as well as time periods where their symptoms are more settled. 


Symptoms can vary from patient to patient and not every patient will experience the same symptoms.  Most commonly they appear as - 

  • Burning and stinging sensations
  • Red flushing areas which can result in permanent redness
  • Spots (papules and pustules)
  • Small blood vessels in the skin becoming visible


However as the condition progresses other symptoms can also develop - 

  • Sensitive skin
  • Rough and dry skin patches
  • Facial swelling
  • Development of plaques 

Diagnosis and Treatment

All patients should make an appointment with their GP to have a confirmed diagnosis if they have persistent symptoms which could be causeed by rosacea. There is no specific test for rosacea, however your GP will be able to make a diagnosis follwing an examination of your skin and asking about the symptoms.


It is important to seek a diagnosis early as this can help prevent the condition from worsening and also rule out other conditions with similar symptoms.

Causes of Rosacea

The exact cause of rosacea is not known, however a number of factors have been linked to the condition.  These include - 

  • Abnormalities in the blood vessels of the face
  • Activation of skin peptides (e.g. through the action of UV light) which may in turn affect your immune system and blood supply.
  • Microscopic mites (usually live harmlessly, however in large numbers may play a role in rosacea)
  • Genetics


There are many known triggers which may make the condition worse. Some of these triggers are -

  • Stress
  • Caffeine
  • Alcohol
  • Sunlight
  • Hot/Cold weather
  • Foods e.g. spicy foods
  • Exercise

Treating Rosacea

Avoiding triggers is key e.g. reducing your intake of drinks containing caffeine or alcohol, using sun screens, avoiding stress and adopting a healthier lifestyle.


There is no known cure for rosacea however treatments are available to help control the symptoms.  Most treatments require to be used for a long period of time, however some can be stopped for short periods if your symptoms improve.  Creams and gels are the most commonly used treatments.  Tablets and capsules, such as long term antibiotics, can also be used.


Topical creams such as Mirvaso can be used safely to reduce the spots and redness however more severe cases might require oral antibiotics. Privatedoc would recommend that you see your own GP if you require any oral antibiotic therapy as these are not suitable for online prescribing.

There are other options such as laser and intense pulse light treatment which your GP can advise you on.

Useful links for patients suffering Rosacea

National Rosacea Society is an American organisation that provides information and support

https://www.rosacea.org/


NHS Choices provides useful information and guidence

https://www.nhs.uk/conditions/rosacea/