Differin Gel

Differin Gel contains the active ingredient adapalene, which is a form of vitamin A used in the treatment of acne.

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Like any other prescription medication you must consult a doctor before using Differin Gel.

PrivateDoc offers a confidential free consultation service that may result in you receiving a prescription for Differin Gel if it is deemed appropriate and Differin Gel can prescribed safely.

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1 gram of gel contains 1mg of adapalene (0.1% w/w)

Topical preparation in a GEL form

The gel is smooth and is white in colour

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What is Differin Gel

Differin Gel has an anti-inflammatory effect and is used to reduce soreness and irritation of the skin caused by mild to moderate acne. It is used on the face, chest or back for acne, where the skin has lots of blackheads, spots and pimples. Differin is only absorbed into the body in very small amounts and has little effect, except on the surface of the skin


Who can use Differin Gel

Differin Gel should be used with caution by people with:

  • Sensitive skin.

Differin Gel should not be used by:-

  • People with known sensitivity or allergy to any ingredients.
  • People with eczema.
  • Pregnant women - in the event of an unexpected pregnancy, treatment should be discontinued

For further information and contraindications please see Patient information leaflet

How to use Differin Gel

Differin Gel should be applied thinly to the affected areas of skin (not just the individual spots) once a day before bedtime.

  • Gently rub the gel into the skin.
  • Wash your hands after applying the medicine.

Treatment Warnings

Important information about Differin Gel:-

  • This preparation is for external use on the skin only.
  • Clean and dry the affected area of skin thoroughly before applying this medicine. Use mild soap and pat rather than rub the skin dry. Using clean fingertips, only apply enough medicine to cover the affected areas of skin lightly.
  • When you first start using this medicine it may cause temporary stinging or a feeling of warmth in the skin. When used correctly, it will usually make your skin slightly red, like mild sunburn. You shouldn't use the medicine any more frequently than directed by your doctor, as this won't make it any more effective or work any quicker. It may also make your skin very red or irritated or start peeling.
  • If you get any severe redness, swelling, itching, burning sensations, blistering, crusting or peeling of your skin after using the medicine, you should apply the medicine less frequently or stop using it temporarily. If the irritation persists you should stop using the medicine completely and consult your doctor.  
  • Avoid getting this gel in contact with the eyes, eyelids, nostrils, mouth, mucous membranes (eg inside of the nose) and broken areas of skin. If you accidentally get the cream/gel on these areas, carefully wash it off with water.

Possible side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Common (affect between 1 in 10 and 1 in 100 people)

  • Dry skin. Burning sensation of the skin. Redness of skin.

For further information and a full list of possible side effects please see Patient information leaflet